LifeMap Integrated Knowledgebase

Effectively navigate the universe of biological entities - genes, proteins, cells, biological pathways and diseases, and the connections between them. LifeMap Sciences’ integrated biomedical knowledgebase includes GeneCards®, the human gene database, MalaCards, the human disease database, and LifeMap Discovery®, the tissues and cells database. 


GeneCards® - The Human Gene Database

GeneCards is a searchable, integrated database of human genes that provides concise genomic related information, on all known and predicted human genes.

GeneCards is a searchable, integrated database of human genes that provides comprehensive, updated, and user-friendly information on all known and predicted human genes. 

GeneCards extracts and integrates gene-related data, including genomic, transcriptomic, proteomic, genetic, clinical, and functional information. This is automatically mined from over 100 carefully selected web sources, thereby allowing one-stop access to a very broad information base. GeneCards overcomes barriers of data format and heterogeneity by using standard nomenclature and approved gene symbols. It presents a rich subset of data for each gene, and provides deep links to the original sources for further scrutiny. Widely used, GeneCards and assists in the understanding of gene-related aspects of biology and medicine. 

 

GeneCards for Academic Institutions >

GeneCards<sup>®</sup>

MalaCards - The Human Disease Database

MalaCards - the human disease database - is an integrated database of human diseases and their annotations, modeled on the architecture and richness of the popular GeneCards database of human genes.

MalaCards is organized into "disease cards" that integrate prioritized information and list numerous known aliases for each disease, along with a variety of annotations and inter-disease connections. Annotations include: symptoms, drugs, articles, genes, clinical trials, related diseases/disorders and more. An automated process extracts and integrates disease-related data from over 60 carefully selected web sources including information gleaned from GeneCards to compile the disease database.

MalaCards integrates both specialized and general disease lists, including rare diseases, genetic diseases, complex disorders and more.

MalaCards disease sections are populated by:

  • Directly interrogating disease resources, to establish integrated disease names, synonyms, summaries, drugs/therapeutics/treatments, clinical features, genetic tests, and anatomical context
  • Searching GeneCards for related publications and associated genes
  • Analyzing disease-associated gene-sets to yield affiliated pathways, phenotypes, compounds, and GO terms
  • Searching within MalaCards for additional related diseases/disorders

 

MalaCards for Academic Institutions >

MalaCards

LifeMap Discovery® - The Cells and Tissues Database

LifeMap Discovery - the cells and tissues database - integrates embryonic development with stem cell biology, molecular, cellular, and anatomical and disease related information. 

LifeMap Discovery is a searchable, integrated database that provides:

  • A detailed description of the developmental ontology of organ/tissues, anatomical compartments and cells
  • Manually curated gene expression at all developmental stages, as well as data extracted from high throughput experiments and large scale in situ databases.
  • Detailed information on signals that regulate cells during development
  • A roadmap for in vitro cell differentiation by matching cells of interest to in vivo entities.
  • The cellular differentiation that occurs during mammalian embryonic development, as well as the concerted differentiation events leading to formation of anatomical compartments within complex organs and tissues.
 

LifeMap Discovery® for Academic Institutions >

 

LifeMap Discovery<sup>®</sup>