MalaCards - the human disease database - is an integrated database of human diseases and their annotations, modeled on the architecture and richness of the popular GeneCards database of human genes.

MalaCards is organized into "disease cards" that integrate prioritized information and list numerous known aliases for each disease, along with a variety of annotations and inter-disease connections. Annotations include: symptoms, drugs, articles, genes, clinical trials, related diseases/disorders and more. An automated process extracts and integrates disease-related data from over 60 carefully selected web sources including information gleaned from GeneCards to compile the disease database.

MalaCards integrates both specialized and general disease lists, including rare diseases, genetic diseases, complex disorders and more.

MalaCards disease sections are populated by:

  • Directly interrogating disease resources, to establish integrated disease names, synonyms, summaries, drugs/therapeutics/treatments, clinical features, genetic tests, and anatomical context
  • Searching GeneCards for related publications and associated genes
  • Analyzing disease-associated gene-sets to yield affiliated pathways, phenotypes, compounds, and GO terms
  • Searching within MalaCards for additional related diseases/disorders


MalaCards for Academic Institutions >